Table 1a: Clinical data, arm-dominant hemiparetic cerebral palsy patients
|
Pt # |
Sex |
Side In. |
Length |
Pregnancy |
Delivery |
Post-natal to age 6 Months |
Upper Limb FG |
Epil. |
Cog. Fun. |
Imaging Results |
|
1 |
M |
L |
term |
N |
N |
N |
2 |
+ |
LD |
B-MCA polymicrogyria |
|
2 |
M |
L |
term |
maternal diabetes |
N |
N |
1 |
+ |
LD |
R-MCA polymicrogyria |
|
3 |
M |
L |
term |
N |
N |
N |
1 |
+ |
LD |
R-MCA polymicrogyria |
|
4 |
F |
L |
term |
2nd trim. bleed |
N |
thrombocyto-penia |
0 |
+ |
LD |
R-MCA infarct, total |
|
5 |
M |
R |
term |
N |
N |
hypoglycemia |
1 |
+ |
LD |
L-MCA infarct, total |
|
6 |
M |
L |
term |
N |
N |
N |
0 |
+ |
LD |
R-MCA infarct, total |
|
7 |
M |
R |
term |
N |
N |
N |
0 |
+ |
MH |
L-MCA infarct, total |
|
8 |
F |
R |
prema. |
N |
N |
N |
0 |
- |
MH |
L-MCA infarct, total* |
|
9 |
F |
R |
term, SGA |
N |
crash C-section |
asphyxia, severe jaundice |
1 |
+ |
N |
L-MCA infarct, frontal lobe |
|
10 |
F |
L |
term, SGA |
N |
N |
N |
0 |
- |
N |
R porencephaly, large frontocentral |
|
11 |
M |
R |
term, SGA |
N |
N |
hydrocephaly at 4 weeks |
1 |
+ |
LD |
L porencephaly large, PVL2 |
|
12 |
M |
L |
prema. |
N |
N |
RDS, grade 4 IVH |
0 |
- |
N |
R porencephaly, small, PVL2 |
|
13 |
M |
R |
prema. |
2nd trim. bleeding |
plac. previa crash sect. |
RDS, asphyxia grade 4 IVH |
0 |
+ |
MH |
L porencephaly, large, frontocentral |
|
14 |
M |
R |
prema. |
N |
N |
RDS asphyxia grade 4 IVH |
0 |
+ |
LD |
L porencephaly, large, frontocentral |
|
15 |
M |
L |
term, SGA |
triplets |
N |
jaundice, sub-durals, shunt |
0 |
+ |
MH |
severe cort./subcort. atrophy R hemisph.; focal atrophy L frontal |
|
16 |
F |
R |
term |
toxemia |
N |
bacterial meningitis |
0 |
+ |
LD |
multicystic
encephalo-malacia |
|
17 |
F |
L |
term |
flu-like ill., 4 mo. |
N |
N |
0 |
+ |
MH |
extensive cort./subcort. atrophy R frontal; bilat. intracran. calcification |
|
18 |
M |
L |
prema. |
toxoplasmosis |
N |
hydrocephaly, jaundice |
0 |
+ |
MH |
pachygyria, colpocephaly, sub-ependymal calcification |
|
19 |
M |
L |
term |
N |
N |
jaundice |
0 |
- |
LD |
large cystic
infarct R |
|
20 |
F |
L |
term |
amniocen. decreased movem |
N |
N |
2 |
- |
LD |
small cystic infarct, R pons* |
Abbreviations: Pt# = patient
number N = normal RDS = respiratory
distress syndrome Side In.
= side of hemiparesis Cog. fun
= cognitive function IVH = intraventricular
hemorrhage FG = functional
grade LD = learning
disability MCA = middle
cerebral artery L = left MH = mentally
handicapped ACA = anterior
cerebral artery R = right SGA = small
for gestational age PVL2 = periventricular
leukomalacia grade 2 (see text) xx * = MRI study,
in addition to CT B = bilateral Epil = epilepsy
present xx
Table 1b: Clinical data, leg-dominant hemiparetic cerebral palsy patients
|
Pt # |
Sex |
Side In. |
Length Gestation |
Pregnancy |
Delivery |
Post-natal to age 6 Months |
Upper Limb FG |
Epil. |
Cog. Fun. |
Imaging Results |
|
21 |
M |
R |
prema. |
N |
N |
RDS |
2 |
- |
N |
L-PVL1 |
|
22 |
F |
L |
term |
N |
N |
N |
2 |
- |
N |
R-PVL1 |
|
23 |
F |
L |
term |
N |
N |
N |
2 |
- |
LD |
R-PVL2 |
|
24 |
F |
R |
term |
N |
N |
N |
2 |
- |
N |
L-PVL2; R-PVL1 |
|
25 |
M |
L |
bdline term |
N |
N |
neonatal jaundice |
2 |
- |
N |
PVL1, bilateral |
|
26 |
M |
L |
term |
N |
N |
neonatal jaundice |
3 |
- |
N |
R-PVL2; L-PVL1 |
|
27 |
M |
R |
term SGA |
toxemia |
N |
neonatal hypoglycemia |
2 |
- |
LD |
PVL2, bilateral, R>L |
|
28 |
F |
R |
term |
bowel obst. 3 mo |
N |
N |
2 |
+ |
N |
L-PVL2; L hippocampal atrophy* |
|
29 |
M |
L |
prema. |
twins |
crash C-section |
asphyxia, RDS, grade 4 IVH |
2 |
- |
MH |
PVL2, bilateral, R>L; porencephaly, small, R |
|
30 |
M |
R |
prema. |
group B strep. |
crash C-section |
N |
2 |
+ |
LD |
L porencephaly, small, frontocentral |
|
31 |
M |
L |
term, SGA |
N |
emerg. C-sect. |
RDS, ventilated anemic |
2 |
- |
N |
cystic lesion, periventricular wm, R trigonal area |
|
32 |
M |
L |
prema. |
twins |
N |
N |
2 |
- |
N |
calc. cyst. gliot. area, R cent. white matter superior to ventr. |
|
33 |
M |
R |
prema. |
N |
N |
grade 2 IVH, L; jaundice |
2 |
- |
N |
focal gliosis, periventr. wm, L hemisph, area of hemorrhage |
|
34 |
M |
R |
term |
N |
crash C-section |
asphyxia, neonatal seizures |
2 |
- |
N |
L-ACA infarct, total |
Abbreviations: Pt# = patient
number N = normal RDS = respiratory
distress syndrome Side In.
= side of hemiparesis Cog. fun
= cognitive function IVH = intraventricular
hemorrhage FG = functional
grade LD = learning
disability MCA = middle
cerebral artery L = left MH = mentally
handicapped ACA = anterior
cerebral artery R = right SGA = small
for gestational age PVL2 = periventricular
leukomalacia grade 2 (see text) xx * = MRI study,
in addition to CT xx Epil = epilepsy
present xx
Table 1c: Clinical data, hemiparetic cerebral palsy patients without clear-cut arm or leg predominance
|
Pt # |
Sex |
Side In. |
Length Gestation |
Pregnancy |
Delivery |
Post-natal to age 6 Months |
Upper Limb FG |
Epil. |
Cog. Fun. |
Imaging Results |
|
35 |
M |
L |
term |
N |
N |
N |
2 |
+ |
LD |
R porencephaly, large central-posterior |
|
36 |
F |
R |
term |
N |
N |
N |
2 |
+ |
LD |
L porencephaly, large, temporo-occipital |
|
37 |
M |
R |
prema. |
N |
N |
RDS, gr. 4 IVH L, gr. 2 R |
2 |
+ |
MH |
L porencephaly, small; large infarct temp.lobe |
|
38 |
F |
R |
term |
1st. trim. bleeding |
N |
N |
1 |
- |
N |
L-PVL2; porencephaly, small |
|
39 |
F |
R |
term |
N |
N |
N |
0 |
- |
N |
L-PVL2 |
|
40 |
F |
L |
prema. SGA |
toxemia, 1st trim. bleeding |
crash C- section |
N |
2 |
- |
LD |
R-PVL2; L-PVL1; mild atrophy; R thalamus* |
|
41 |
M |
L |
term |
H.zoster inf. 8 mo. |
N |
neonatal jaundice |
2 |
- |
N |
multiple small calcified cysts, R internal capsule & basal ganglia |
Abbreviations: Pt# = patient
number N = normal RDS = respiratory
distress syndrome Side In.
= side of hemiparesis Cog. fun
= cognitive function IVH = intraventricular
hemorrhage FG = functional
grade LD = learning
disability MCA = middle
cerebral artery L = left MH = mentally
handicapped ACA = anterior
cerebral artery R = right SGA = small
for gestational age PVL2 = periventricular
leukomalacia grade 2 (see text) xx * = MRI study,
in addition to CT xx Epil = epilepsy
present xx
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